American Board of Internal Medicine (ABIM) Certification Practice Exam

Disable ads (and more) with a membership for a one time $2.99 payment

Study for the ABIM Certification Exam. Use flashcards and multiple choice questions, with hints and explanations for each. Get ready to succeed!

Each practice test/flash card set has 50 randomly selected questions from a bank of over 500. You'll get a new set of questions each time!

Practice this question and more.

Which of the following is least associated with FSGS?

Diabetes Mellitus
Obesity
Hypertension
HIV infection

The correct answer is: Diabetes Mellitus

Focal segmental glomerulosclerosis (FSGS) is a complex and multifactorial kidney disease characterized by scarring in some segments of the kidney's filtering units. Among the listed conditions, diabetes mellitus is more commonly related to the development of various kidney diseases, including diabetic nephropathy, which can lead to FSGS. Obesity, hypertension, and HIV infection are all established risk factors known to contribute to the development or exacerbation of FSGS. Obesity is linked to a state of glomerular hyperfiltration and inflammation, often leading to a higher incidence of kidney disease. Hypertension is frequently seen in patients with FSGS as it can lead to further damage to the glomeruli. HIV infection has been identified as a strong risk factor for FSGS, particularly in individuals with the virus who may develop kidney complications as part of their systemic illness. Therefore, diabetes mellitus is least associated with FSGS compared to obesity, hypertension, and HIV infection, which have more direct connections to the disease's pathophysiology and progression.