American Board of Internal Medicine (ABIM) Certification Practice Exam

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Which medication is approved for the treatment of anxiety disorders?

Olanzapine
Quetiapine
Buspirone
Bupropion

The correct answer is: Buspirone

Buspirone is the approved medication for the treatment of anxiety disorders. It is classified as an anxiolytic and is specifically indicated for the management of generalized anxiety disorder (GAD). Buspirone works by acting on serotonin receptors, particularly the 5-HT1A receptor, which helps to alleviate anxiety symptoms without the sedative effects commonly associated with benzodiazepines. While the other medications listed are used in various psychiatric conditions, they do not have the same specific approval for anxiety disorders. Olanzapine and quetiapine are atypical antipsychotics primarily used for schizophrenia and bipolar disorder, though they may have anxiolytic effects. Bupropion is an antidepressant that primarily treats major depressive disorder and smoking cessation, but it is not indicated for anxiety disorders and may even exacerbate anxiety in some individuals. Thus, Buspirone stands out as the appropriate choice for the treatment of anxiety disorders due to its targeted action and regulatory approval.