American Board of Internal Medicine (ABIM) Certification Practice Exam

What is the common menstrual issue faced by women with vWD?

1. Heavy menstrual bleeding

2. Irregular cycles

3. Clotting during menstruation

4. Lighter than normal periods

The correct answer is: Heavy menstrual bleeding

Women with von Willebrand disease (vWD) commonly experience heavy menstrual bleeding, also known as menorrhagia. This condition arises due to a deficiency or dysfunction of von Willebrand factor, which plays a crucial role in platelet adhesion and stabilization of clotting factors in the blood. As a result, women with vWD have a compromised ability to form effective blood clots, leading to prolonged and excessive bleeding during menstruation. Heavy menstrual bleeding can significantly impact the quality of life, cause anemia, and pose various health risks. It is essential for healthcare providers to recognize this connection between vWD and menorrhagia to ensure appropriate management and treatment for affected individuals. Addressing heavy menstrual bleeding may involve the use of hormonal therapies, tranexamic acid, or desmopressin to manage symptoms and reduce bleeding episodes.