American Board of Internal Medicine (ABIM) Certification Practice Exam

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What is the age range for individuals who can receive the live-attenuated influenza vaccine via nasal mist?

  1. 1 to 50 years

  2. 2 to 49 years

  3. 5 to 65 years

  4. 10 to 60 years

The correct answer is: 2 to 49 years

The live-attenuated influenza vaccine (LAIV), administered via nasal mist, is specifically indicated for use in individuals between the ages of 2 and 49 years. This age range is established based on studies that demonstrate safety and efficacy in this group. The vaccine is contraindicated for use in younger children, particularly those under 2 years old, due to an increased risk of wheezing and respiratory complications. Additionally, it is not recommended for older adults, as those over 49 years may have a different immune response to the live vaccine and are generally at higher risk for complications from influenza. This means that individuals in the 2 to 49 age range are best suited to benefit from the nasal mist form of the vaccine, as they are more likely to mount an effective immune response and less likely to experience adverse effects compared to those outside this range. Other age ranges mentioned in the incorrect options do not align with the established recommendations for the administration of the live-attenuated influenza vaccine, thereby confirming the correctness of the choice defining the age eligibility as 2 to 49 years.